PRP and PRF are trending terms in regenerative aesthetics — but what do they really mean? In this post we’ll explain what PRF and PRP are, how they differ, their common uses, and which might suit your goals best.
PRP (Platelet-Rich Plasma) is made by drawing your blood, spinning it in a centrifuge with anticoagulant, and extracting the platelet-rich plasma containing growth factors. Discovery Laser Skin Care Clinic+2WellMedica+2
PRF (Platelet-Rich Fibrin) is a newer method that uses a slower centrifuge process without anticoagulant, producing a fibrin matrix that releases growth factors over time. True Contour Medical+3Discovery Laser Skin Care Clinic+3cosmedhairskin.com.au+3
| Feature | PRP | PRF |
|---|---|---|
| Use of anticoagulant | Yes | No |
| Speed of growth factor release | Faster / more immediate | Slower, sustained release |
| Matrix / scaffold | Less structured | Fibrin matrix supports lasting effect |
| Longevity of effect | Good | Often superior in long-term support Discovery Laser Skin Care Clinic+2WellMedica+2 |
Facial rejuvenation (under eyes, cheeks)
Scar improvement (acne scars, surgical scars)
Hair restoration / scalp treatments
Combined with microneedling or as standalone injections
PRP is more established and cost effective.
PRF may offer deeper, longer-lasting effects because of its sustained release.
Some areas (e.g. under-eyes) may benefit more from PRF due to gentler, continuous support.
The procedural technique, patient condition, centrifuge protocol, and injection depth all influence outcomes.
PRP and PRF are exciting regenerative tools that leverage your own biology for skin revival. Interested in exploring which is right for you—especially in sensitive zones like under-eyes or mixed into microneedling? Book a consultation with us now and let’s unlock your skin’s potential.
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